Leg heaviness developing later in the day is commonly associated with reduced peripheral circulation, prolonged sitting or standing, endothelial stress, fluid retention patterns, mild vascular congestion, inflammatory signaling, and muscular fatigue within the lower extremities. The sensation may involve aching, pressure, fullness, tightness, sluggish movement, or fatigue in the calves, ankles, thighs, or feet. Reduced nitric oxide signaling, impaired endothelial responsiveness, elevated sodium intake, oxidative stress, dehydration, prolonged inactivity, and metabolic inflammation may contribute to reduced vascular efficiency and venous return from the lower limbs. Peripheral circulation relies on healthy endothelial cells lining the blood vessels. These cells regulate vascular tone, nitric oxide production, inflammatory signaling, blood fluidity, and oxygen delivery to tissues. Chronic oxidative stress, inflammatory dietary patterns, low potassium intake, excessive processed food intake, and inactivity may impair endothelial signaling and contribute to circulatory discomfort patterns. Venous pressure accumulation during prolonged standing or sedentary behavior may further increase sensations of heaviness and fatigue within the legs. A whole food plant-based dietary pattern emphasizing nitrate-rich vegetables, antioxidant-rich fruits, hydration-supportive foods, legumes, herbs, and potassium-rich plant foods may help support endothelial function, nitric oxide pathways, vascular flexibility, and circulatory efficiency. Leafy greens, beetroot, citrus fruits, berries, tomatoes, pomegranate, garlic, and polyphenol-rich foods naturally contain compounds associated with vascular signaling support and oxidative balance. Fiber-rich foods may also support metabolic stability and inflammatory regulation linked to circulatory health. Plant foods rich in flavonoids, anthocyanins, nitrates, carotenoids, vitamin C compounds, potassium, magnesium, and polyphenols may help support endothelial resilience, blood vessel relaxation, cellular antioxidant defenses, and healthy microcirculation. Maintaining hydration, minimizing excess sodium from processed foods, supporting regular movement, and consuming potassium-rich whole plant foods may help support healthy fluid balance and lower extremity comfort. Whole grains, legumes, vegetables, fruits, seeds, and herbs provide nutritional compounds associated with vascular integrity, nitric oxide production, and circulatory efficiency. Circulatory stress may also involve inflammatory signaling pathways including NF-κB activity, oxidative stress responses, endothelial nitric oxide regulation, and vascular inflammatory mediators. Supporting antioxidant-rich whole foods while minimizing highly processed foods and inflammatory dietary compounds may help support healthy endothelial biology, tissue oxygenation, and peripheral circulation patterns associated with end-of-day leg heaviness.