Restless Legs Syndrome (RLS) is a neurological and sensory-motor condition characterized by uncomfortable sensations in the legs accompanied by a strong urge to move. Symptoms commonly intensify during periods of inactivity, especially in the evening or nighttime hours, and may interfere with sleep quality, recovery, concentration, and daytime energy levels. Research has associated RLS with altered dopamine signaling, iron metabolism imbalance, oxidative stress, mitochondrial dysfunction, impaired nerve signaling, inflammation, endothelial dysfunction, and disruptions in circadian rhythm regulation. Functional nutrient insufficiencies involving iron, magnesium, folate, and vitamin B6 have also been observed in some individuals with recurring symptoms. Circulatory and metabolic health can influence symptom severity. Reduced microvascular blood flow, endothelial irritation, elevated inflammatory signaling, and impaired oxygen delivery may contribute to increased leg discomfort, twitching, and nighttime restlessness. Diet patterns high in processed foods, excess sodium, added sugars, stimulants, artificial additives, and inflammatory compounds may further aggravate neurological stress responses and sleep disruption. Poor hydration and electrolyte imbalance may also contribute to muscular excitability and nighttime cramping sensations associated with RLS. A whole-food plant-based dietary pattern emphasizing mineral-rich vegetables, legumes, seeds, berries, leafy greens, and antioxidant-dense foods may help support neurological balance, vascular function, and mitochondrial energy pathways involved in healthy nerve activity. Foods naturally rich in magnesium, potassium, folate, iron, polyphenols, and nitric oxide-supportive compounds may assist healthy circulation, cellular oxygen delivery, and antioxidant defense systems. Fiber-rich plant foods additionally support glucose regulation and gut microbiome signaling, both of which influence inflammatory pathways and nervous system function. Leafy greens such as spinach, kale, swiss chard, and collard greens provide folate, magnesium, potassium, carotenoids, and antioxidant flavonoids involved in neuromuscular stability. Legumes including lentils, black beans, and chickpeas contribute iron, magnesium, amino acids, and slow-digesting carbohydrates supportive of steady metabolic energy production. Seeds such as pumpkin seeds, chia seeds, flax seeds, and sesame seeds provide magnesium, zinc, manganese, and plant compounds associated with vascular and neurological support. Berries, cherries, citrus fruits, and green tea provide polyphenols including quercetin, anthocyanins, catechins, rutin, and EGCG that participate in oxidative stress regulation and endothelial function. Circadian rhythm disruption, chronic stress signaling, sedentary behavior, dehydration, and excessive intake of stimulant-containing beverages may worsen nighttime neurological excitability. Emphasizing hydration, balanced mineral intake, antioxidant-rich whole foods, stable glucose patterns, and anti-inflammatory dietary patterns may help support healthier sleep architecture, muscular relaxation, and nervous system recovery associated with RLS support.