Salt sensitivity refers to a physiological pattern in which blood pressure responds strongly to sodium intake due to altered kidney sodium handling, vascular tone dysregulation, endothelial stress, fluid retention, and neurohormonal signaling changes. Individuals with salt sensitivity often experience greater fluid-volume expansion, vascular resistance, and endothelial dysfunction when consuming sodium-dense processed foods with inadequate potassium-rich plant intake. The kidneys play a central role in regulating sodium excretion, electrolyte balance, renin signaling, aldosterone activity, and blood pressure stability. Potassium-rich whole plant foods may help support normal sodium excretion and vascular relaxation. Potassium participates in membrane potential regulation, smooth muscle function, endothelial nitric oxide signaling, and hydration balance. Magnesium also contributes to vascular tone regulation, insulin signaling support, and neuromuscular stability. Fiber-rich whole foods may additionally support metabolic balance, microbiome signaling, inflammatory regulation, and endothelial resilience associated with healthy circulatory function. Highly processed foods commonly contain elevated sodium concentrations while lacking protective minerals, fiber, flavonoids, nitrate-containing vegetables, carotenoids, and polyphenols naturally found in whole plant foods. Chronic oxidative stress, vascular inflammation, endothelial dysfunction, insulin resistance, obesity-related metabolic stress, and impaired nitric oxide signaling may worsen salt-sensitive blood pressure responses. Excess sodium intake combined with low potassium intake may also increase arterial stiffness, vascular contraction signaling, and fluid retention pathways. A whole food plant-based dietary pattern emphasizing leafy greens, legumes, fruits, cruciferous vegetables, potassium-rich vegetables, nitrate-containing vegetables, seeds, and antioxidant-rich whole foods may help support vascular flexibility, endothelial nitric oxide production, electrolyte balance, and circulatory resilience. Beetroot, spinach, kale, banana, sweet potato, avocado_hass, lentils, black beans, citrus fruits, and tomato provide potassium, magnesium, flavonoids, carotenoids, nitrates, vitamin C compounds, and polyphenols associated with vascular support pathways. Foods rich in quercetin, catechins, anthocyanins, carotenoids, and sulforaphane may additionally support antioxidant defense systems associated with endothelial health. Hydration status, potassium intake, magnesium intake, insulin sensitivity, and endothelial nitric oxide signaling are interconnected with sodium regulation biology. Maintaining dietary patterns centered around minimally processed whole plant foods while reducing ultra-processed sodium-heavy foods may support healthier vascular responses associated with salt sensitivity and circulatory stress.