Obstructive sleep apnea is a sleep-related breathing condition characterized by repeated narrowing or collapse of the upper airway during sleep. Excess body weight, central fat accumulation, metabolic dysfunction, chronic inflammation, oxidative stress, and impaired glucose regulation are strongly associated with increased severity of airway obstruction and nighttime oxygen fluctuation. Research has shown that diets high in processed foods, saturated fats, excess sodium, refined carbohydrates, and calorie-dense meals are linked to higher systemic inflammation, insulin resistance, endothelial dysfunction, and disrupted sleep architecture. Excess visceral fat surrounding the neck and airway can mechanically narrow breathing passages while also contributing to inflammatory signaling that affects respiratory stability during sleep. Whole-food plant-based nutrition patterns emphasizing vegetables, legumes, fruits, mushrooms, herbs, seeds, and intact whole grains are associated with improved body composition, lower inflammatory burden, healthier vascular function, improved insulin signaling, and reduced oxidative stress. Increased dietary fiber intake is associated with improved satiety regulation, glycemic balance, and healthier weight management patterns. Plant foods naturally provide potassium, magnesium, folate, vitamin C, polyphenols, carotenoids, and flavonoids that support endothelial nitric oxide activity, mitochondrial energy balance, and inflammatory regulation. Dietary patterns rich in cruciferous vegetables, leafy greens, berries, legumes, oats, mushrooms, and nitrate-containing vegetables may support metabolic pathways associated with vascular flexibility, oxygen utilization, and circadian rhythm stability. High-antioxidant foods may help reduce oxidative stress generated during intermittent oxygen fluctuation associated with disrupted nighttime breathing. Polyphenol-rich foods including berries, green tea, pomegranate, broccoli, kale, and turmeric contain compounds studied for interactions with inflammatory mediators including NF-κB, oxidative stress signaling, endothelial dysfunction, and metabolic pathways linked with obesity-related inflammation. Weight reduction through high-fiber, low-energy-density whole plant foods has been associated with reductions in body mass index, waist circumference, inflammatory signaling, and metabolic strain. Whole grains and legumes help support slower glucose absorption and improved insulin sensitivity while minimizing post-meal glycemic instability. Evening dietary excess, highly processed foods, excess sodium intake, and refined sugar exposure may worsen fluid retention, metabolic stress, and disrupted sleep quality. A structured whole-food plant-based dietary pattern emphasizing hydration, fiber-rich meals, intact carbohydrates, mineral-rich vegetables, and antioxidant-dense foods may support healthier metabolic function, body weight regulation, circulatory health, respiratory resilience, and improved sleep quality patterns associated with obstructive sleep apnea support strategies.