Acute Myeloid Leukemia (Adult)

Main Grouping: Hematologic

Organ: Bone marrow, blood

Description
Acute myeloid leukemia (AML) is the most common acute leukemia in adults, accounting for approximately 80 percent of adult acute leukemias. In the United State…

Adrenal Cortical Carcinoma

Main Grouping: Endocrine

Organ: Adrenal glands,endocrine system,retroperitoneum

Description
Adrenocortical carcinoma (ACC) is a rare but highly aggressive malignancy of the adrenal cortex with an incidence of approximately 0.7 to 2 cases per million p…

Adrenal Cortical Carcinoma – Non-Viral Adult Form

Main Grouping: Endocrine

Organ: Adrenal Cortex

Description
Adrenal cortical carcinoma is a rare malignant tumor of the adrenal cortex, the steroid-producing outer layer of the adrenal gland. Adult ACC is biologically d…

Adrenal Medullary Tumor (Adult Pheochromocytoma-like)

Main Grouping: Endocrine

Organ: Adrenal Medulla

Description
Pheochromocytoma (PHEO) is a catecholamine-secreting neuroendocrine tumor of the adrenal medulla arising from chromaffin cells of neural crest origin. Paragang…

Adult Retinoblastoma (Retinal Tumor)

Main Grouping: Ophthalmologic

Organ: Eye,retina,optic nerve,central nervous system

Description
Retinoblastoma is a malignant intraocular tumor arising from retinal progenitor cells and is defined at the molecular level by biallelic inactivation of the RB…

Anal Squamous Cell Carcinoma – Non-Viral Emphasis

Main Grouping: Digestive

Organ: Anal canal

Description
Anal squamous cell carcinoma (ASCC) is a rare gastrointestinal malignancy arising from the squamous and transitional epithelium of the anal canal, representing…

Appendiceal Adenocarcinoma

Main Grouping: Digestive

Organ: Appendix/peritoneum

Description
Appendiceal adenocarcinoma is a rare malignancy of glandular epithelial origin arising from the mucosa of the vermiform appendix. Estimated incidence is approx…

Basal Cell Carcinoma (Skin, Non-Melanoma)

Main Grouping: Integumentary

Organ: Skin,epidermis,hair follicle unit

Description
Basal cell carcinoma (BCC) is the most common human cancer and the most common malignant skin tumor, accounting for approximately 80 to 90 percent of all non-m…

Bile Duct (Intrahepatic) Cancer Extension

Main Grouping: Digestive

Organ: Intrahepatic bile ducts,liver,hepatobiliary system.

Description
Intrahepatic cholangiocarcinoma (iCCA), also designated as bile duct cancer with intrahepatic extension, is a primary malignancy of the biliary epithelium aris…

Bladder Cancer

Main Grouping: Urinary

Organ: Urinary bladder,urothelium,genitourinary system

Description
Bladder cancer is a common malignancy of the urinary system, ranking ninth in global cancer incidence with an estimated 573,278 new cases and 212,536 deaths in…

Bladder Squamous Cell Carcinoma

Main Grouping: Urinary

Organ: Bladder

Description
Bladder Squamous Cell Carcinoma (SCC) is a malignant epithelial neoplasm arising from the urothelium of the urinary bladder that demonstrates a pure squamous c…

Bladder Urothelial Carcinoma – Extension

Main Grouping: Urinary

Organ: Bladder

Description
Bladder urothelial carcinoma is the tenth most common cancer globally and the sixth most common cancer in the United States by incidence. An estimated 83,190 n…

Bone Cancer (Osteosarcoma)

Main Grouping: Musculoskeletal

Organ: Bone,skeletal system

Description
Osteosarcoma (OS) is the most frequent primary bone cancer in children and adolescents and the third most frequent primary bone cancer in adults. Primary bone …

Bone Chondrosarcoma

Main Grouping: Musculoskeletal

Organ: Bone (cartilage-producing)

Description
Chondrosarcoma is the second most common primary malignant bone tumor, comprising approximately 20 to 27 percent of all primary malignant bone tumors in the Un…

Bone Osteosarcoma – Adult Extension

Main Grouping: Musculoskeletal

Organ: Bone

Description
Osteosarcoma (OS) is the most common primary malignant bone tumor and the third most frequent cancer in children and adolescents after leukemia and brain tumor…

Brain Astrocytoma – Adult Low-Grade

Main Grouping: Nervous System

Organ: Brain

Description
Adult low-grade astrocytoma (CNS WHO Grade 2, IDH-mutant) is a diffusely infiltrating primary brain tumor that predominantly affects young to middle-aged adult…

Brain Cancer (Glioblastoma)

Main Grouping: Nervous System

Organ: Brain,central nervous system,cerebral hemispheres

Description
Glioblastoma (GBM), classified as WHO Grade IV astrocytoma, is the most common and most lethal primary brain tumor in adults. Its frequency represents 12 to 15…

Brain Meningioma (Benign, Space-Occupying)

Main Grouping: Nervous System

Organ: Meninges

Description
Brain meningioma is the most common primary intracranial tumor in adults and develops from the meninges, the protective membranes surrounding the brain and spi…

Brain Oligodendroglioma – Adult Form

Main Grouping: Nervous System

Organ: Brain

Description
Oligodendroglioma (IDH-mutant and 1p/19q-codeleted) is one of three molecularly defined adult diffuse glioma entities recognized by the 2021 WHO Classification…

Brainstem Glioma (Adult Non-Pediatric)

Main Grouping: Nervous System

Organ: Brainstem

Description
Adult brainstem glioma (ABG) represents a distinct subset of gliomas arising within the brainstem structures — the pons, midbrain, and medulla oblongata — in p…

Breast Cancer

Main Grouping: Endocrine/Reproductive

Organ: Breast, Lymph Nodes

Description
Breast cancer is the most commonly diagnosed malignancy among women worldwide and a leading cause of cancer-related mortality. It originates primarily in the d…

Breast Ductal Carcinoma In Situ (DCIS)

Main Grouping: Reproductive

Organ: Breast

Description
Breast Ductal Carcinoma In Situ (DCIS) is a non-invasive, pre-invasive neoplastic proliferation of epithelial cells confined within the ductal-lobular system o…

Breast Lobular Carcinoma – Extension

Main Grouping: Reproductive

Organ: Breast

Description
Invasive lobular carcinoma (ILC) is the second most common invasive breast cancer subtype, accounting for approximately 10 to 15 percent of all invasive breast…

Cervical Adenocarcinoma – Non-Viral Pathway Focus

Main Grouping: Reproductive

Organ: Cervix

Description
Cervical adenocarcinoma (CAC) is the second most common histological subtype of cervical cancer, accounting for approximately 20 to 25 percent of all cervical …

Cervical Cancer

Main Grouping: Reproductive

Organ: Cervix uteri,female reproductive tract,lower genital tract

Description
Cervical cancer is the fourth most common cancer diagnosed in women worldwide. In the GLOBOCAN 2018 study, cervical cancer was ranked fourth in terms of both i…

Cervical Squamous Cell Carcinoma – Non-Viral Emphasis

Main Grouping: Reproductive

Organ: Cervix

Description
Cervical squamous cell carcinoma is the most common histologic form of cervical cancer and develops from malignant squamous epithelial cells of the cervix, mos…

Cholangiocarcinoma (Bile Duct)

Main Grouping: Digestive

Organ: Intra/extrahepatic bile ducts

Description
Cholangiocarcinoma (CCA) is the second most common primary hepatic malignancy after hepatocellular carcinoma and the most common malignancy of the biliary trac…

Chronic Lymphocytic Leukemia (CLL)

Main Grouping: Hematologic

Organ: Blood, lymph nodes

Description
Chronic lymphocytic leukemia (CLL) is the most common leukemia in Western countries, accounting for approximately 25 to 30 percent of all leukemias in the Unit…

Colorectal Cancer

Main Grouping: Digestive

Organ: Colon, Rectum

Description
Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second leading cause of cancer death globally, representing a major public health b…

Colorectal Cancer – Metastatic Focus

Main Grouping: Digestive

Organ: Colon, Rectum (with liver/lung mets)

Description
Metastatic colorectal cancer (mCRC) is the advanced stage of colorectal cancer in which the primary tumor has spread to distant organs, most commonly the liver…

Endometrial (Uterine) Carcinoma – Extension

Main Grouping: Reproductive

Organ: Uterus

Description
Endometrial carcinoma is the most commonly diagnosed cancer of the female reproductive tract in the United States, the fourth most common cancer in women in th…

Esophageal Adenocarcinoma

Main Grouping: Digestive

Organ: Esophagus (lower)

Description
Esophageal adenocarcinoma (EAC) is a primary malignancy of the distal esophagus and gastroesophageal junction arising from columnar-lined Barrett's esophagus t…

Esophageal Cancer

Main Grouping: Digestive

Organ: Esophagus,upper gastrointestinal tract,gastroesophageal junction

Description
Esophageal cancer ranks among the ten most common cancers worldwide and is the eighth leading cause of cancer-related mortality globally. In 2022, China alone …

Esophageal Small Cell Carcinoma

Main Grouping: Digestive

Organ: Esophagus

Description
Primary small cell carcinoma of the esophagus (PSCCE) is one of the rarest and most lethal malignancies of the esophagus, accounting for approximately 0.5 to 2…

Esophageal Squamous Cell Carcinoma – Upper

Main Grouping: Digestive

Organ: Esophagus

Description
Esophageal Squamous Cell Carcinoma of the upper esophagus (upper ESCC) originates in the stratified squamous epithelium lining the cervical and upper thoracic …

Extrahepatic Cholangiocarcinoma – Extension

Main Grouping: Digestive

Organ: Extrahepatic bile ducts

Description
Extrahepatic cholangiocarcinoma (eCCA) encompasses perihilar cholangiocarcinoma (pCCA/Klatskin tumor) and distal extrahepatic cholangiocarcinoma (dCCA), arisin…

Gallbladder Adenocarcinoma – Extension

Main Grouping: Digestive

Organ: Gallbladder

Description
Gallbladder adenocarcinoma (GBC) is the most common and most lethal biliary tract malignancy, representing approximately 80 to 90 percent of all biliary tract …

Gallbladder Cancer

Main Grouping: Digestive

Organ: Gallbladder,biliary tract,hepatobiliary system

Description
Gallbladder cancer (GBC) is an aggressive malignancy of the biliary tract characterized by poor prognosis due to subtle early symptoms leading to diagnosis at …

Gallbladder Squamous Cell Carcinoma

Main Grouping: Digestive

Organ: Gallbladder

Description
Gallbladder squamous cell carcinoma (GB-SCC) is a rare and aggressive histological subtype of gallbladder carcinoma — the most common biliary tract malignancy …

Gastric (Stomach) Adenocarcinoma – Extension

Main Grouping: Digestive

Organ: Stomach,gastric mucosa

Description
Gastric adenocarcinoma (GC) is the dominant histological subtype of stomach cancer, accounting for over 90 percent of all stomach cancers. Stomach cancer is th…

Gastric Signet Ring Cell Carcinoma

Main Grouping: Digestive

Organ: Stomach

Description
Gastric signet ring cell carcinoma (SRCC) is a morphologically and molecularly distinctive subtype of gastric adenocarcinoma characterized by tumor cells with …

Head & Neck SCC (Oral Cavity/Pharynx)

Main Grouping: Respiratory/Digestive

Organ: Oral cavity,pharynx,oropharynx,larynx,head and neck mucosal epithelium

Description
Head and neck squamous cell carcinoma (HNSCC) is the sixth most frequent cancer type worldwide, with over 870,000 new cases and 440,000 deaths reported in 2020…

Hodgkin Lymphoma

Main Grouping: Lymphatic

Organ: Lymphatic system,lymph nodes,spleen,bone marrow,mediastinum

Description
Hodgkin lymphoma (HL) is one of the most frequently occurring lymphoid malignancies in young people in the Western world, with an annual incidence of approxima…

Hodgkin Lymphoma – Adult Form

Main Grouping: Hematologic

Organ: Lymphatic System

Description
Hodgkin lymphoma (HL) is a lymphoid malignancy arising from mature B lymphocytes of germinal center origin that is characterized by the pathognomonic Hodgkin a…

Kidney Cancer (Chromophobe RCC)

Main Grouping: Urinary

Organ: Kidneys

Description
Chromophobe renal cell carcinoma (chRCC) is the third most common subtype of renal cell carcinoma, representing approximately 5 to 7 percent of all RCC diagnos…

Kidney Cancer (Renal Papillary Carcinoma)

Main Grouping: Urinary

Organ: Kidneys

Description
Papillary renal cell carcinoma (pRCC) is the second most common histological subtype of renal cell carcinoma, accounting for approximately 15 to 20 percent of …

Kidney Clear Cell Carcinoma – Extension

Main Grouping: Urinary

Organ: Kidney

Description
Clear cell renal cell carcinoma (ccRCC) is the most common form of kidney cancer and the most common urological malignancy after bladder and prostate cancer in…

Laryngeal Cancer

Main Grouping: Respiratory

Organ: Larynx,upper aerodigestive tract,head and neck mucosal epithelium

Description
Laryngeal cancer is the eleventh most common malignancy worldwide and one of the most common types of head and neck cancer. Laryngeal squamous cell carcinoma (…

Laryngeal Carcinoma – Extension

Main Grouping: Respiratory

Organ: Larynx

Description
Laryngeal carcinoma is the second most common cancer of the head and neck globally, after oral cavity cancers, and represents the most common cancer of the lar…

Laryngeal Squamous Cell Carcinoma (Non-Viral)

Main Grouping: Respiratory

Organ: Larynx

Description
Laryngeal squamous cell carcinoma (LSCC) is the most common malignancy of the larynx, representing approximately 95 percent of all laryngeal cancers and approx…

Liver Angiosarcoma (Vascular)

Main Grouping: Digestive

Organ: Liver

Description
Liver angiosarcoma, also called primary hepatic angiosarcoma when it begins in the liver, is a rare malignant vascular tumor derived from hepatic endothelial c…

Liver Cancer (HCC)

Main Grouping: Digestive

Organ: Liver,hepatobiliary system

Description
Hepatocellular carcinoma (HCC) constitutes approximately 90 percent of all primary liver cancers and ranks as a leading cause of cancer-related death worldwide…

Liver Fibrolamellar Carcinoma

Main Grouping: Digestive

Organ: Liver

Description
Fibrolamellar hepatocellular carcinoma (FLC) is an exceptionally rare primary liver malignancy, accounting for approximately 1 to 5 percent of all hepatocellul…

Liver Intrahepatic Cholangiocarcinoma – Advanced

Main Grouping: Digestive

Organ: Liver

Description
Intrahepatic cholangiocarcinoma (iCCA) is the second most common primary liver malignancy after hepatocellular carcinoma (HCC), representing approximately 10 t…

Lung Adenocarcinoma – Extension

Main Grouping: Respiratory

Organ: Lungs

Description
Lung cancer is the leading cause of cancer-related death globally, accounting for approximately 2.21 million new cases and 1.80 million deaths in 2022 accordin…

Lung Cancer (NSCLC)

Main Grouping: Respiratory

Organ: Lungs

Description
Non-small cell lung cancer (NSCLC) is the most common major category of lung cancer, accounting for approximately 85 percent of all lung cancer diagnoses. It e…

Lung Cancer (SCLC)

Main Grouping: Respiratory

Organ: Lungs

Description
Small cell lung cancer (SCLC) is a high-grade malignant neoplasm that accounts for approximately 13 to 15 percent of all lung cancer diagnoses, representing th…

Lung Large Cell Carcinoma (Non-Smoker Pathway)

Main Grouping: Respiratory

Organ: Lungs

Description
Lung large cell carcinoma (LCC) in the non-smoker pathway is a rare and aggressive subtype of non-small cell lung cancer (NSCLC) defined by the absence of squa…

Lung Squamous Cell Carcinoma – Non-Smoking Focus

Main Grouping: Respiratory

Organ: Lungs

Description
Lung squamous cell carcinoma (LUSC) is the second most common histological subtype of non-small cell lung cancer (NSCLC) after lung adenocarcinoma, representin…

Multiple Myeloma

Main Grouping: Lymphatic/Hematologic

Organ: Bone marrow,skeletal system,blood,kidneys,immune system

Description
Multiple myeloma (MM) is a malignant neoplasm of terminally differentiated plasma cells that accumulate in the bone marrow, produce monoclonal immunoglobulin (…

Nasopharyngeal Cancer

Main Grouping: Respiratory

Organ: Nasopharynx,head and neck,upper respiratory tract,lymphatic system

Description
Nasopharyngeal carcinoma (NPC) is a malignancy arising from the epithelium of the nasopharynx with a highly distinctive geographic distribution, molecular biol…

Nasopharyngeal Carcinoma – Non-Viral Adult Form

Main Grouping: Respiratory

Organ: Nasopharynx

Description
Nasopharyngeal Carcinoma – Non-Viral Adult Form is an epithelial cancer of the nasopharynx, the upper throat region located behind the nasal cavity and above t…

Non-Hodgkin Lymphoma

Main Grouping: Lymphatic

Organ: Lymphatic system,lymph nodes,spleen,bone marrow,

Description
Non-Hodgkin lymphoma (NHL) represents the most common hematologic malignancy and the seventh most common cancer overall in the United States. Approximately 80,…

Non-Hodgkin Lymphoma – Diffuse Large B-Cell

Main Grouping: Hematologic

Organ: Lymphatic System

Description
Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma worldwide, representing approximately 30 to 40 percent of all NHL cases. In the U…

Oral Cavity Squamous Cell Carcinoma – Extension

Main Grouping: Respiratory/Digestive

Organ: Mouth, tongue, floor of mouth

Description
Oral cavity squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity and accounts for more than 90 percent of all oral cancers, represen…

Oropharyngeal Cancer

Main Grouping: Respiratory/Digestive

Organ: Oropharynx,head and neck,oral cavity,upper aerodigestive tract

Description
Oropharyngeal cancer (OPC) is a malignancy arising from the squamous epithelium of the oropharynx, a region of the throat encompassing the base of tongue, tons…

Ovarian Clear Cell Carcinoma – Extension

Main Grouping: Reproductive

Organ: Ovary/Peritoneum

Description
Ovarian clear cell carcinoma (OCCC) is a biologically distinct subtype of epithelial ovarian cancer characterized by clear glycogen-rich cytoplasm,hobnail morp…

Ovarian Epithelial Carcinoma – Extension

Main Grouping: Endocrine/Reproductive

Organ: Ovaries, Peritoneum

Description
Ovarian epithelial carcinoma (OEC) is the most common and lethal type of ovarian cancer, accounting for approximately 90 percent of all ovarian malignancies an…

Pancreatic Acinar Cell Carcinoma

Main Grouping: Digestive

Organ: Pancreas

Description
Pancreatic acinar cell carcinoma (PACC) is a rare malignant pancreatic neoplasm arising from the acinar cells of the exocrine pancreas, representing approximat…

Pancreatic Adenocarcinoma – Advanced Extension

Main Grouping: Digestive

Organ: Pancreas

Description
Pancreatic ductal adenocarcinoma (PDAC) is the most lethal major solid malignancy, with a 5-year overall survival of approximately 12 to 13 percent across all …

Pancreatic Neuroendocrine Tumor (Non-Viral)

Main Grouping: Digestive

Organ: Pancreas

Description
Pancreatic neuroendocrine tumors (PanNETs) are uncommon endocrine malignancies arising from the hormone-producing cells of the pancreatic islets. Although they…

Pancreatic Neuroendocrine Tumor (PNET)

Main Grouping: Endocrine

Organ: Pancreas

Description
Pancreatic neuroendocrine tumors (PNETs) represent approximately 1 to 2 percent of all pancreatic neoplasms but account for a disproportionately high fraction …

Parathyroid Carcinoma

Main Grouping: Endocrine

Organ: Neck (parathyroid glands)

Description
Parathyroid carcinoma is the rarest endocrine malignancy, representing less than 1 percent of all cases of primary hyperparathyroidism and approximately 0.005 …

Parotid Acinic Cell Carcinoma

Main Grouping: Head & Neck

Organ: Salivary glands (parotid predominant)

Description
Parotid acinic cell carcinoma (AciCC) is the second most common malignant salivary gland tumor after mucoepidermoid carcinoma, representing approximately 6 to …

Penile Squamous Cell Carcinoma – Non-Viral

Main Grouping: Reproductive

Organ: Penis

Description
Penile squamous cell carcinoma (PSCC) is a rare urological malignancy affecting the squamous epithelium of the penis, representing approximately 0.4 to 0.6 per…

Pituitary Adenoma – Endocrine Active

Main Grouping: Endocrine

Organ: Pituitary Gland

Description
Pituitary adenomas (also called pituitary neuroendocrine tumors or PitNETs under the 2022 WHO classification) are the most common intracranial neoplasm after g…

Pleural Mesothelioma – Lifestyle/Metabolic Focus

Main Grouping: Respiratory

Organ: Pleura (lung lining)

Description
Malignant pleural mesothelioma (MPM) is a rare but highly aggressive primary cancer arising from the mesothelial cells lining the pleural cavities of the lungs…

Pleural Synovial Sarcoma (Metabolic Emphasis)

Main Grouping: Respiratory

Organ: Pleura (lung lining)

Description
Primary pleural synovial sarcoma (PPSS) is an exceptionally rare soft tissue malignancy arising directly from the pleural cavity or thoracic wall, representing…

Prostate Adenocarcinoma – Extension

Main Grouping: Reproductive

Organ: Prostate

Description
Prostate adenocarcinoma is the most common non-skin cancer in men in the United States and the second leading cause of cancer death in American men. An estimat…

Prostate Cancer

Main Grouping: Endocrine/Reproductive

Organ: Prostate

Description
Prostate cancer is the most commonly diagnosed solid tumor in men in the United States and the second leading cause of cancer death among American men, followi…

Prostate Small Cell Carcinoma (Non-Hormonal Focus)

Main Grouping: Reproductive

Organ: Prostate

Description
Prostate small cell carcinoma (PSCNC), also designated prostate neuroendocrine carcinoma of small cell type, is a histologically and molecularly distinct and h…

Salivary Gland Carcinoma (Mucoepidermoid)

Main Grouping: Digestive/Head & Neck

Organ: Parotid/submandibular/sublingual glands

Description
Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor, representing approximately 30 to 40 percent of all salivary gland malignancie…

Skin Basal Cell Carcinoma – Extension

Main Grouping: Integumentary

Organ: Skin

Description
Skin basal cell carcinoma is the most common keratinocyte carcinoma and the most common human malignancy overall. It usually grows slowly and remains localized…

Skin Melanoma – Metastatic Extension

Main Grouping: Integumentary

Organ: Skin

Description
Melanoma is the most lethal form of skin cancer, accounting for approximately 4 to 5 percent of all skin cancer diagnoses but approximately 75 percent of all s…

Skin Merkel Cell Carcinoma – Non-Viral Adult Form

Main Grouping: Integumentary

Organ: Skin

Description
Merkel cell carcinoma (MCC) is an uncommon but highly aggressive primary neuroendocrine carcinoma of the skin. It is the second most lethal skin cancer after m…

Skin Squamous Cell Carcinoma (Non-Melanoma)

Main Grouping: Integumentary

Organ: Skin

Description
Skin Squamous Cell Carcinoma (SCC) is a common form of non-melanoma skin cancer that develops from squamous cells, the flat cells that make up much of the epid…

Small Intestine Adenocarcinoma

Main Grouping: Digestive

Organ: Small Intestine

Description
Small Intestine Adenocarcinoma (SBA) is a malignancy arising from the glandular epithelial lining of the small bowel, which comprises the duodenum, jejunum, an…

Soft Tissue Liposarcoma

Main Grouping: Musculoskeletal

Organ: Adipose/soft tissue

Description
Liposarcoma is the most common soft tissue sarcoma in adults, comprising approximately 20 percent of all soft tissue sarcomas globally. In the United States, s…

Soft Tissue Sarcoma

Main Grouping: Musculoskeletal

Organ: Soft tissues including fat (adipose), muscle (skeletal and smooth), fibrous connective tissue, peripheral nerves, blood vessels, and synovial tissue.

Description
Soft tissue sarcomas (STS) are a rare, complex, and heterogeneous group of malignant mesenchymal neoplasms with over 150 different histological subtypes. STS c…

Stomach Lymphoma (MALT Type)

Main Grouping: Digestive

Organ: Stomach

Description
Gastric MALT lymphoma (extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue of the stomach) is the most common primary gastric lymphom…

Synovial Sarcoma

Main Grouping: Musculoskeletal

Organ: Periarticular soft tissues

Description
Synovial sarcoma is the most common soft tissue sarcoma in adolescents and young adults, accounting for approximately 5 to 10 percent of all soft tissue sarcom…

Testicular Cancer

Main Grouping: Reproductive

Organ: Testes,male reproductive system,urological system

Description
Testicular germ cell tumors (TGCTs) represent the most common cancer in young men aged 15 to 35 years and the incidence of TGCTs is increasing worldwide. Overa…

Testicular Germ Cell Tumor – Adult (Non-Viral)

Main Grouping: Reproductive

Organ: Testes

Description
Testicular germ cell tumors (TGCTs) of adults are the most common solid malignancy in males aged 15 to 45 years and represent the most curable of all solid can…

Thymic Carcinoma (Adult)

Main Grouping: Immune/Respiratory

Organ: Anterior mediastinum (thymus)

Description
Thymic carcinoma is a rare and aggressive primary malignant epithelial tumor of the thymus arising from thymic epithelial cells, representing approximately 20 …

Thyroid Cancer

Main Grouping: Endocrine

Organ: Thyroid gland,endocrine system,neck

Description
Thyroid cancer is the most common endocrine malignancy, accounting for 3.4 percent of all cancers diagnosed annually, and its global incidence has increased su…

Thyroid Follicular Carcinoma

Main Grouping: Endocrine

Organ: Thyroid

Description
Thyroid follicular carcinoma (FTC) is the second most common thyroid carcinoma after papillary thyroid carcinoma (PTC), representing approximately 10 to 15 per…

Thyroid Medullary Carcinoma

Main Grouping: Endocrine

Organ: Thyroid

Description
Medullary thyroid carcinoma (MTC) is a rare neuroendocrine malignancy arising from the calcitonin-secreting parafollicular C-cells of the thyroid gland. MTC ac…

Thyroid Papillary Carcinoma – Extension

Main Grouping: Endocrine

Organ: Thyroid

Description
Papillary thyroid carcinoma (PTC) is the most common form of thyroid cancer and accounts for approximately 80 to 85 percent of all thyroid malignancies diagnos…

Triple-Negative Breast Cancer (TNBC)

Main Grouping: Endocrine/Reproductive

Organ: Breast (Mammary Gland)

Description
Triple-negative breast cancer (TNBC) is defined by the simultaneous absence of estrogen receptor (ER), progesterone receptor (PR), and HER2 overexpression/ampl…

Uterine Sarcoma (Leiomyosarcoma)

Main Grouping: Reproductive

Organ: Uterus (myometrium)

Description
Uterine leiomyosarcoma is a rare but highly aggressive mesenchymal malignancy arising from the smooth muscle tissue of the uterine myometrium. Although it acco…

Uveal Melanoma (Ocular)

Main Grouping: Ophthalmologic

Organ: Eye (iris/ciliary body/choroid)

Description
Uveal melanoma (UM) is the most common primary intraocular malignant tumor in adults, arising from melanocytes located within the uveal tract of the eye, which…

Vaginal Squamous Cell Carcinoma – Non-Viral

Main Grouping: Reproductive

Organ: Vagina

Description
Primary vaginal squamous cell carcinoma (VSCC) is an exceptionally rare gynecologic malignancy comprising approximately 1 to 3 percent of all female genital tr…

Vulvar Squamous Cell Carcinoma – Non-Viral

Main Grouping: Reproductive

Organ: Vulva

Description
Vulvar squamous cell carcinoma (VSCC) is a rare gynecologic malignancy representing approximately 3 to 5 percent of all female genital tract cancers and approx…